Cohort profile: the clinical 'Psoriasis in Adolescents' (PIA) cohort in Denmark.

ABSTRACT:

Purpose

Psoriasis is a chronic inflammatory skin disease that frequently debuts in childhood and adolescence. We wished to determine environmental and genetic risk factors for the development of psoriasis in children and adolescents, as well as to investigate debut type, trigger factors, course of disease, nature and influence of stress related to both child and family and risk factors for comorbidity. The 'Psoriasis in Adolescents' (PIA) cohort will provide data on the relationship between psoriasis and, respectively, genetic disposition, early-life exposures, quality of life and comorbidity.

Participants

The PIA cohort is nested in the large general population Danish National Birth Cohort (DNBC). We invited 390 adolescents with psoriasis and corresponding maternally predis

SUBMITTER: Blegvad C 

PROVIDER: S-EPMC6773347 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature