3D Printing of Hot Dog-Like Biomaterials with Hierarchical Architecture and Distinct Bioactivity.

ABSTRACT: Hierarchical structure has exhibited an important influence in the fields of supercapacitors, catalytic applications, and tissue engineering. The hot dog, a popular food, is composed of bread and sausage with special structures. In this study, inspired by the structure of a hot dog, the strategy of combining direct ink writing 3D printing with bidirectional freezing is devised to prepare hot dog-like scaffolds with hierarchical structure. The scaffolds are composed of hollow bioceramic tubes (mimicking the "bread" in hot dogs, pore size: ≈1 mm) embedded by bioceramic rods (mimicking the "sausage" in hot dogs, diameter: ≈500 µm) and the sausage-like bioceramic rods possess uniformly aligned lamellar micropores (lamellar pore size: ≈30 µm). By mimicking the functions of hierarchical structur

SUBMITTER: Li T 

PROVIDER: S-EPMC6774059 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature