Glucose control in the ICU.

ABSTRACT:

Purpose of review

Critically ill patients usually develop hyperglycemia, which is associated with adverse outcome. Controversy exists whether the relationship is causal or not. This review summarizes recent evidence regarding glucose control in the ICU.

Recent findings

Despite promising effects of tight glucose control in pioneer randomized controlled trials, the benefit has not been confirmed in subsequent multicenter studies and one trial found potential harm. This discrepancy could be explained by methodological differences between the trials rather than by a different case mix. Strategies to improve the efficacy and safety of tight glucose control have been developed, including the use of computerized treatment algorithms.

Summary

The ideal blood glucose target re

SUBMITTER: Gunst J 

PROVIDER: S-EPMC6774765 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature