The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome.

ABSTRACT:

Purpose

There are no internationally agreed upon clinical guidelines as to which women with gynecological cancer would benefit from Lynch syndrome screening or how best to manage the risk of gynecological cancer in women with Lynch syndrome. The Manchester International Consensus Group was convened in April 2017 to address this unmet need. The aim of the Group was to develop clear and comprehensive clinical guidance regarding the management of the gynecological sequelae of Lynch syndrome based on existing evidence and expert opinion from medical professionals and patients.

Methods

Stakeholders from Europe and North America worked together over a two-day workshop to achieve consensus on best practice.

Results

Guidance was developed in four key areas: (1) whether women

SUBMITTER: Crosbie EJ 

PROVIDER: S-EPMC6774998 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature