Development and Validation of a Model to Predict Acute Kidney Injury in Hospitalized Patients With Cirrhosis.

ABSTRACT: OBJECTIVES:Acute kidney injury (AKI) is a common complication in hospitalized patients with cirrhosis which contributes to morbidity and mortality. Improved prediction of AKI in this population is needed for prevention and early intervention. We developed a model to identify hospitalized patients at risk for AKI. METHODS:Admission data from a prospective cohort of hospitalized patients with cirrhosis without AKI on admission (n = 397) was used for derivation. AKI development in the first week of admission was captured. Independent predictors of AKI on multivariate logistic regression were used to develop the prediction model. External validation was performed on a separate multicenter cohort (n = 308). RESULTS:In the derivation cohort, the mean age was 57 years, the Model for End-Stage Liv

SUBMITTER: Patidar KR 

PROVIDER: S-EPMC6775340 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature