Hepatic steatosis in patients with acromegaly.

ABSTRACT:

Objective

Comorbid NAFLD is increasingly being diagnosed in patients with diabetes and nondiabetic endocrinopathies. The aim of this study was to assess hepatic steatosis noninvasively by transient elastography in patients with acromegaly.

Design

A cross-sectional study including 22 patients with acromegaly.

Methods

Hepatic steatosis was quantified using controlled attenuation parameter (CAP) during elastography. Anthropometric measurements were obtained, serum liver function tests and lipid and hormone profiles were measured, and prosteatogenic gene variants were genotyped using standard assays.

Results

In total, 41% of patients were women (mean age 60 ± 14.7 years, mean BMI 31.2 ± 4.6 kg/m²). Hepatic steatosis, as defined by CAP > 248 dB/m, was pre

SUBMITTER: Koutsou-Tassopoulou A 

PROVIDER: S-EPMC6775446 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature