SCDevDB: A Database for Insights Into Single-Cell Gene Expression Profiles During Human Developmental Processes.

ABSTRACT: Single-cell RNA-seq studies profile thousands of cells in developmental processes. Current databases for human single-cell expression atlas only provide search and visualize functions for a selected gene in specific cell types or subpopulations. These databases are limited to technical properties or visualization of single-cell RNA-seq data without considering the biological relations of their collected cell groups. Here, we developed a database to investigate single-cell gene expression profiling during different developmental pathways (SCDevDB). In this database, we collected 10 human single-cell RNA-seq datasets, split these datasets into 176 developmental cell groups, and constructed 24 different developmental pathways. SCDevDB allows users to search the expression profiles of the inte

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6775478 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature