Survival impacts of extent of resection and adjuvant radiotherapy for the modern management of high-grade meningiomas.

ABSTRACT:

Purpose

We aim to investigate the impacts of extent of resection and adjuvant radiotherapy on survival of high-grade meningiomas (WHO grade II-III) according to modern diagnosis and management.

Methods

Patients with high-grade meningiomas were identified in the Surveillance Epidemiology and End Results (SEER) database between 2000 and 2015 and used for survival analysis. Propensity score matching (PSM) was conducted to reduce selection bias. Another 92 patients from Sun Yat-sen University Cancer Center (SYSUCC) were used for validation.

Results

530 patients were enrolled from SEER. Patients with gross total resection (GTR) had no significantly different overall survival (OS) compared with those with subtotal resection (STR), even after performing PSM between these two

SUBMITTER: Li D 

PROVIDER: S-EPMC6775537 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature