Amino acids as wetting agents: surface translocation by Porphyromonas gingivalis.

ABSTRACT: Our understanding of how oral microbiota adapt in response to changes in their surroundings remains limited. This is particularly true of the slow-growing anaerobes that persist below the gum line. Here, we report that the oral anaerobe Porphyromonas gingivalis strain 381 can surface translocate when sandwiched between two surfaces. We show that during movement, this bacterium alters its metabolism, specifically side products of arginine utilization including citrulline and ornithine accumulated in the translocating cells; while arginine, N-acetyl-arginine, and the polyamine putrescine, which is produced from arginine were consumed. In addition, our results indicate that movement requires modification of the surrounding environment via proteolysis, cell dispersion, cell-on-cell rolling, an

SUBMITTER: Moradali MF 

PROVIDER: S-EPMC6775972 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature