Safety and Effectiveness of Chemotherapy for Metastatic Esophageal Cancer in a Community Hospital in Brazil.

ABSTRACT:

Purpose

Despite epidemiologic and molecular differences between esophageal and stomach cancers, most published studies have included patients with either disease in a metastatic scenario. We evaluated the safety and effectiveness of chemotherapy in patients with metastatic esophageal cancer in the community setting.

Patients and methods

We performed a retrospective cohort study of patients with synchronous metastatic esophageal cancer treated at a public hospital between 2008 and 2016. Patients were grouped according to a prescribed chemotherapy protocol: platinum and taxane (group A); platinum and irinotecan (group B); platinum and fluoropyrimidine (group C); and without platinum (group D).

Results

Of the 1,789 patients with esophageal cancer treated, we included 397

SUBMITTER: Victor CR 

PROVIDER: S-EPMC6775989 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature