Macrogeographic genetic structure of Lutzomyia longipalpis complex populations using Next Generation Sequencing.

ABSTRACT: Lutzomyia longipalpis is the main vector of Leishmania infantum, the causative agent of visceral leishmaniasis in the Neotropical realm. Its taxonomic status has been widely discussed once it encompasses a complex of species. The knowledge about the genetic structure of insect vector populations helps the elucidation of components and interactions of the disease ecoepidemiology. Thus, the objective of this study was to genotypically analyze populations of the Lu. longipalpis complex from a macrogeographic perspective using Next Generation Sequencing. Polymorphism analysis of three molecular markers was used to access the levels of population genetic structure among nine different populations of sand flies. Illumina Amplicon Sequencing Protocol® was used to identify possible polymorphic sit

SUBMITTER: Casaril AE 

PROVIDER: S-EPMC6776309 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature