Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture.

ABSTRACT: BACKGROUND AND OBJECTIVE:Trial registration is widely endorsed as it is considered not only to enhance transparency and quality of reporting but also to help safeguard against outcome reporting bias and probably spin, known as specific reporting that could distort the interpretation of results thus mislead readers. We planned to investigate the current registration status of recently published randomized controlled trials (RCTs) of acupuncture, outcome reporting bias in the prospectively registered trials, and the association between trial registration and presence of spin and methodological factors in acupuncture RCTs. METHODS:Acupuncture RCTs published in English in recent 5 years (January 2013 to December 2017) were searched in PubMed, Cochrane Central Register of Controlled Trials, and

SUBMITTER: Won J 

PROVIDER: S-EPMC6776391 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature