Changes in serum markers of patients with PCOS during consecutive clomiphene stimulation cycles: a retrospective study.

ABSTRACT:

Background

A retrospective case-control study was performed to evaluate whether PCOS-specific serum markers would change in women with polycystic ovary syndrome (PCOS) during the course of two consecutive cycles of clomiphene citrate (CC)-stimulation, which did not lead to a pregnancy.

Methods

Anovulatory PCOS patients who underwent two consecutive CC-cycles (n = 41) and anovulatory PCOS controls who chose an observational approach for two months (n = 24) were included in the study. The main outcome measures were levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), anti-Mullerian hormone (AMH), total testosterone, androstenedione, and sexual hormone binding globulin (SHBG).

Results

In the control group, PCOS-specific serum parameters did not change

SUBMITTER: Hager M 

PROVIDER: S-EPMC6777034 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature