Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

General anesthesia during thrombectomy for acute ischemic stroke has been associated with poor neurological outcome in nonrandomized studies. Three single-center randomized trials reported no significantly different or improved outcomes for patients who received general anesthesia compared with procedural sedation.

Objective

To detect differences in functional outcome at 3 months between patients who received general anesthesia vs procedural sedation during thrombectomy for anterior circulation acute ischemic stroke.

Data source

MEDLINE search for English-language articles published from January 1, 1980, to July 31, 2019.

Study selection

Randomized clinical trials of adults with a National Institutes of Health Stroke Scale score of at least 10 and an

SUBMITTER: Schonenberger S 

PROVIDER: S-EPMC6777267 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature