Time-Varying Outcomes With the Absorb Bioresorbable Vascular Scaffold During 5-Year Follow-up: A Systematic Meta-analysis and Individual Patient Data Pooled Study.

ABSTRACT:

Importance

Bioresorbable scaffolds were designed to provide clinical benefits after their complete bioresorption. Prior studies demonstrated early risks with the Absorb polymeric bioresorbable vascular scaffold (BVS). Whether this risk profile changes over time during the course of its bioresorption is unknown.

Objective

To examine outcomes of the first-generation BVS before and after 3 years, the point of its complete bioresorption in animals.

Data sources

We searched MEDLINE and the Cochrane database, conference proceedings, and public websites for relevant studies.

Study selection

Eligible studies were randomized clinical trials of BVS vs metallic drug-eluting stents in patients with coronary artery disease with at least 5-year follow-up. Four trials of BVS

SUBMITTER: Stone GW 

PROVIDER: S-EPMC6777269 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature