Mechanically Induced Periprosthetic Osteolysis: A Systematic Review.

ABSTRACT:

Background

Peri-prosthetic bone loss can result from chemical, biological, and mechanical factors. Mechanical stimulation via fluid pressure and flow at the bone-implant interface may be a significant cause. Evidence supporting mechanically induced osteolysis continues to grow, but there is no synthesis of published clinical and basic science data.

Questions/purposes

We sought to review the literature on two questions: (1) What published evidence supports the concept of mechanically induced osteolysis? (2) What is the proposed mechanism of mechanically induced osteolysis, and does it differ from that of particle-induced osteolysis?

Methods

A systematic review was performed of the PubMed and Web of Science databases. Additional relevant articles were recommended by the

SUBMITTER: McArthur BA 

PROVIDER: S-EPMC6778158 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature