Colorectal Cancer: An Update on Treatment Options and Future Perspectives.

ABSTRACT: Throughout the years, colorectal cancer has steadily become a global health problem. While other types of cancers have seen a decline in cases because of screening and vaccination programs, colorectal cancer has risen become the third most diagnosed cancer worldwide and, more worryingly, the second leading cancer-related cause of death. The introduction of targeted therapy has been widely considered a major paradigm shift in the treatment of colorectal cancer, which agents such as bevacizumab and cetuximab quickly becoming mainstay options in the treatment of locally advanced or metastatic disease. However, this type of treatment has also shown its limitations, with limited or no benefit for a large portion of the patients. With more and more knowledge being gathered on the molecular mecha

SUBMITTER: Florescu-Tenea RM 

PROVIDER: S-EPMC6778294 | biostudies-literature | 2019 Apr-Jun

REPOSITORIES: biostudies-literature