Posttraumatic Stress Disorder and Incident Infections: A Nationwide Cohort Study.

ABSTRACT:

Background

It is unknown whether posttraumatic stress disorder (PTSD) is associated with incident infections. This study's objectives were to examine (1) the association between PTSD diagnosis and 28 types of infections and (2) the interaction between PTSD diagnosis and sex on the rate of infections.

Methods

The study population consisted of a longitudinal nationwide cohort of all residents of Denmark who received a PTSD diagnosis between 1995 and 2011, and an age- and sex-matched general population comparison cohort. We fit Cox proportional hazards regression models to examine associations between PTSD diagnosis and infections. To account for multiple estimation, we adjusted the hazard ratios (HRs) using semi-Bayes shrinkage. We calculated interaction contrasts to assess th

SUBMITTER: Jiang T 

PROVIDER: S-EPMC6779341 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature