Long-term Prognostic Value of Estimated Plasma Volume in Heart Failure with Preserved Ejection Fraction.

ABSTRACT: Plasma volume, estimated by several indirect methods, has been viewed as a biological surrogate for intravascular fluid status. The clinical implication of estimated plasma volume status (ePVS) for long term outcomes in heart failure with preserved ejection fraction (HFpEF) remains unclear. We investigate the prognostic value of ePVS calculated by Strauss formula and its association with cardiovascular events and mortality in a prospective HFpEF cohort. There were 449 individuals met the inclusion criteria of our cohort. Estimated plasma volume variation (ΔePVS) and its instantaneous derivatives were calculated by the Strauss formula. Our study endpoints were events of heart failure hospitalization and mortality. Kaplan-Meier estimates and Cox regression analysis were applied to determine

SUBMITTER: Huang CY 

PROVIDER: S-EPMC6779908 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature