A higher incidence of smooth endoplasmic reticulum clusters with aromatase inhibitors.

ABSTRACT:

Purpose

This study aimed to analyze whether a regimen of aromatase inhibitor (AI) could reduce the occurrence of smooth endoplasmic reticulum clusters (sERCs) in oocytes.

Methods

The AI and the clomiphene citrate (CC) regimens were compared, regarding the sERC (+) rates and the serum estradiol and progesterone levels on the date of hCG administration, and the duration of AI, CC, and hMG administration.

Results

The occurrence of sERCs in oocytes from patients treated with AI was significantly higher than that in oocytes from those treated with CC. Both the serum estradiol and progesterone levels were found to be significantly higher in sERC (+) than in sERC (-) cycles. With regard to the CC cycles, no significant differences were detected. The duration of AI and hMG ad

SUBMITTER: Saito H 

PROVIDER: S-EPMC6780026 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature