Probiotics for the Prophylaxis of Migraine: A Systematic Review of Randomized Placebo Controlled Trials.

ABSTRACT: Migraine is a common and disabling neurological condition with a complex etiology. Recent advances in the understanding of the gut microbiome have shown the role of gut micro-organisms in disease outcomes for distant organs-including the brain. Interventions targeting the gut microbiome have been shown to be effective in multiple neurological diagnoses, but there is little research into the role of the microbiome in migraine. This systematic review seeks to assess the current research landscape of randomized placebo controlled trials utilizing probiotic interventions as migraine prophylaxis. Searches were conducted of scientific databases including PubMed, MEDLINE, and the Cochrane Library, following PRISMA guidelines. Of 68 screened studies, 2 were eligible for analysis. Due to methodolog

SUBMITTER: Naghibi MM 

PROVIDER: S-EPMC6780403 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature