[Expression profile of miR-501-5p in lung adenocarcinoma patients from Xuanwei area].

ABSTRACT:

Objective

To investigate the relationship between miR-501-5p expression and the clinicopathological factors in patients with lung adenocarcinoma in Xuanwei area.

Methods

Surgical specimens of lung adenocarcinoma and paired adjacent tissues from 24 patients with lung adenocarcinoma from Xuanwei area were examined for miR-501-5p expression using microRNA microarray technique and qPCR. Chi-square test was used to analyze the association of miR-501-5P expression with the clinicopathological characteristics of the patients. Multiple regression analysis was performed to analyze the association of miR-501-5p expression with the patients' gender, age, tumor stage, and preoperative CEA level.

Results

MicroRNA microarray analysis and qPCR validation results revealed significant

SUBMITTER: Chen S 

PROVIDER: S-EPMC6780435 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature