Choroidal Patterns in Stargardt Disease: Correlations with Visual Acuity and Disease Progression.

ABSTRACT: To identify different choroidal patterns in Stargardt disease (STGD) and to assess their clinical correlates. 100 STGD eyes (29 males; mean age 42.6 ± 16.5 years) and 100 control eyes (29 males; mean age 43.2 ± 8.5 years) were included. Optical coherence tomography (OCT) and OCT angiography (OCTA) images were obtained. Four different choroidal patterns, quantitative OCT and OCTA parameters were assessed and statistically analyzed. The main outcome was the correlation between each choroidal pattern and anatomical and functional retinal status. Furthermore, we assessed structural and best corrected visual acuity (BCVA) changes of each STGD subgroup after one-year. Mean BCVA was 0.63 ± 0.44 LogMAR for STGD patients and 0.0 ± 0.0 LogMAR for controls (p < 0.01). All quantitative parameters appe

SUBMITTER: Arrigo A 

PROVIDER: S-EPMC6780607 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature