Amine Responsive Poly(lactic acid) (PLA) and Succinic Anhydride (SAh) Graft-Polymer: Synthesis and Characterization.

ABSTRACT: Amines are known to react with succinic anhydride (SAh), which in reactions near room temperature, undergoes a ring opening amidation reaction to form succinamic acid (succinic acid-amine). In this work, we propose to form an amine-responsive polymer by grafting SAh to a poly(lactic acid) (PLA) backbone, such that the PLA can provide chemical and mechanical stability for the functional SAh during the amidation reaction. Grafting is performed in a toluene solution at mass content from 10 wt% to 75 wt% maleic anhydride (MAh) (with respect to PLA and initiator), and films are then cast. The molecular weight and thermal properties of the various grafted polymers are measured by gel permeation chromatography and differential scanning calorimetry, and the chemical modification of these materials

SUBMITTER: Lopera-Valle A 

PROVIDER: S-EPMC6780798 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature