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Acute Effects of Transdermal Administration of Jojoba Oil on Lipid Metabolism in Mice.


ABSTRACT: Background and objectives: Aroma therapy is a complementary therapy using essential oils diluted with carrier oils. Jojoba oils have been widely used as carrier oils. However, limited information is available regarding their effects on blood biochemical parameters. This study aimed to investigate the effect of transdermal administration of jojoba oil on blood biochemical parameters in mice. Materials and Methods: Eight-week-old male hairless mice were randomly divided into naïve control and treatment groups. In the treatment group, mice were topically administered 4 μL of jojoba oil, per gram of body weight, on the dorsa 30 min before euthanasia. Thereafter, serum biochemical parameters were assayed, and gene expression was analyzed in various tissues via a real-time polymerase chain react

SUBMITTER: Matsumoto Y 

PROVIDER: S-EPMC6780807 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature