Cognitive impairments in patients with persistent symptoms attributed to Lyme disease.

ABSTRACT:

Background

Persistent symptoms attributed to Lyme borreliosis often include self-reported cognitive impairment. However, it remains unclear whether these symptoms can be substantiated by objective cognitive testing.

Methods

For this observational study, cognitive performance was assessed in 280 adults with persistent symptoms attributed to Lyme borreliosis (as part of baseline data collected for the Dutch PLEASE study). Cognitive testing covered the five major domains: episodic memory, working memory / attention, verbal fluency, information-processing speed and executive function. Patients' profiles of test scores were compared to a large age-, education- and sex-adjusted normative sample using multivariate normative comparison. Performance validity was assessed to detect su

SUBMITTER: Berende A 

PROVIDER: S-EPMC6781329 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature