Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia.

ABSTRACT:

Objectives

Physical frailty (or loss of physiologic reserve) is associated with cognitive impairment and dementia. Subjective cognitive decline (SCD) may represent early pathologic changes of dementia. The association between these disease markers is unclear.

Design

Cross-sectional analysis.

Setting

Community-based participants from the Vanderbilt Memory & Aging Project.

Participants

A total of 306 older adults with normal cognition (NC; n = 174) or mild cognitive impairment (MCI; n = 132).

Measurements

Frailty was measured using standard methods, and a composite frailty score was calculated. SCD was quantified using the Everyday Cognition Scale (ECog; total score and four domain scores). Objective cognition was assessed with the Montreal Cognitive Asses

SUBMITTER: Gifford KA 

PROVIDER: S-EPMC6781867 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature