Natural Variation and Genetic Determinants of Caenorhabditis elegans Sperm Size.

ABSTRACT: The diversity in sperm shape and size represents a powerful paradigm to understand how selection drives the evolutionary diversification of cell morphology. Experimental work on the sperm biology of the male-hermaphrodite nematode Caenorhabditis elegans has elucidated diverse factors important for sperm fertilization success, including the competitive superiority of larger sperm. Yet despite extensive research, the molecular mechanisms regulating C. elegans sperm size and the genetic basis underlying natural variation in sperm size remain unknown. To address these questions, we quantified male sperm size variation of a worldwide panel of 97 genetically distinct C. elegans strains, allowing us to uncover significant genetic variation in male sperm size. Aiming to

SUBMITTER: Gimond C 

PROVIDER: S-EPMC6781899 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature