Ontology highlight
ABSTRACT:
SUBMITTER: Vinh PT
PROVIDER: S-EPMC6784239 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Vinh Pham Thi PT Shinohara Yui Y Yamada Akifumi A Duc Hoang Minh HM Nakayama Motokazu M Ozawa Tadahiro T Sato Jun J Masuda Yoshimitsu Y Honjoh Ken-Ichi KI Miyamoto Takahisa T
Toxins 20190829 9
Shiga toxin-producing enterohaemorrhagic <i>Escherichia coli</i> (EHEC<i>)</i> O157:H7 is an important foodborne pathogen. Baicalein (5,6,7-trihydroxylflavone), a flavone isolated from the roots of Scutellaria baicalensis, is considered as a potential antibacterial agent to control foodborne pathogens. Among seven compounds selected by in silico screening of the natural compound database, baicalein inhibited the cytotoxicity of both Shiga toxins 1 and 2 (Stx1 and Stx2) against Vero cells after p ...[more]