Developmental Trajectories of Infants With Multiplex Family Risk for Autism: A Baby Siblings Research Consortium Study.

ABSTRACT:

Importance

Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with different genetic etiologies. Prospective examination of familial-risk infants informs understanding of developmental trajectories preceding ASD diagnosis, potentially improving early detection.

Objective

To compare outcomes and trajectories associated with varying familial risk for ASD across the first 3 years of life.

Design, setting, and participants

This longitudinal, prospective cohort study used data from 11 sites in the Baby Siblings Research Consortium database. Data were collected between 2003 and 2015. Infants who were younger siblings of children with ASD were followed up for 3 years. Analyses were conducted in April 2018. Of the initial 1008 infants from the database

SUBMITTER: McDonald NM 

PROVIDER: S-EPMC6784852 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature