Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2.

ABSTRACT: Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans^1,2. Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host^3-6. We used metagenomic and metatranscriptomic sequencing of single host individuals, plus metaproteomic and imaging analyses, to show that the placozoan Trichoplax sp. H2 lives in symbiosis with two intracellular bacteria. One symbiont forms an undescribed genus in the Midichloriaceae (Rickettsiales)^7,8 and has a genomic repertoire similar to that of rickettsial parasites^9,10, but does not seem to express key genes for energy parasitism. Correlative image analyses and three-dimensional electron tomography

SUBMITTER: Gruber-Vodicka HR 

PROVIDER: S-EPMC6784892 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature