Environmental Chemicals and Autism: A Scoping Review of the Human and Animal Research.

ABSTRACT:

Background

Estimates of autism prevalence have increased dramatically over the past two decades. Evidence suggests environmental factors may contribute to the etiology of the disorder.

Objectives

This scoping review aimed to identify and categorize primary research and reviews on the association between prenatal and early postnatal exposure to environmental chemicals and the development of autism in epidemiological studies and rodent models of autism.

Methods

PubMed was searched through 8 February 2018. Included studies assessed exposure to environmental chemicals prior to 2 months of age in humans or 14 d in rodents. Rodent studies were considered relevant if they included at least one measurement of reciprocal social communicative behavior or repetitive and stereoty

SUBMITTER: Pelch KE 

PROVIDER: S-EPMC6785231 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature