Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2.

ABSTRACT:

Purpose

To investigate the progression characteristics of ellipsoid zone (EZ) loss in eyes with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements, and their relevance for visual acuity.

Methods

Participants were selected from the MacTel Study cohort. Linear and area measurements of EZ loss were performed in Spectral-Domain Optical Coherence Tomograph (SD-OCT) volume scans. Progression characteristics and correlations between linear and area measurements were analysed using linear mixed effects models.

Results

A total of 134 eyes of 70 patients were included (85 eyes with follow-up, mean 4.7 years, range: 1.4-8 years). Ellipsoid zone (EZ) loss significantly progressed at a mean annual increment of 0.057 mm² (p = 0.005). The

SUBMITTER: Pauleikhoff D 

PROVIDER: S-EPMC6785352 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature