Antithrombotic treatment after coronary artery bypass graft surgery: systematic review and network meta-analysis.

ABSTRACT:

Objective

To assess the effects of different oral antithrombotic drugs that prevent saphenous vein graft failure in patients undergoing coronary artery bypass graft surgery.

Design

Systematic review and network meta-analysis.

Data sources

Medline, Embase, Web of Science, CINAHL, and the Cochrane Library from inception to 25 January 2019. ELIGIBILITY CRITERIA: for selecting studies Randomised controlled trials of participants (aged ≥18) who received oral antithrombotic drugs (antiplatelets or anticoagulants) to prevent saphenous vein graft failure after coronary artery bypass graft surgery.

Main outcome measures

The primary efficacy endpoint was saphenous vein graft failure and the primary safety endpoint was major bleeding. Secondary endpoints were myoca

SUBMITTER: Solo K 

PROVIDER: S-EPMC6785742 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature