Commonly Initiated Opioids and Risk of Fracture Hospitalizations in United States Nursing Homes.

ABSTRACT:

Objectives

The aim of this study was to estimate the comparative safety of initiating commonly used opioids among older, long-stay United States nursing home residents with fracture hospitalizations.

Methods

We conducted a new-user retrospective cohort study of nursing home residents initiating short-acting oxycodone, hydrocodone, or tramadol by merging the 2011-2013 Minimum Data Set 3.0 to Medicare hospitalization and pharmacy claims. Residents (≥ 65 years, no cancer or hospice use) contributed treatment episodes (> 120 days with no prior opioid claims) and were followed for 180 days until incident fracture hospitalization (hip, femur, humerus, pelvis, radius/ulna), death (competing risk), treatment changes (e.g., discontinuation), or administrative censoring. Competing ris

SUBMITTER: Hunnicutt JN 

PROVIDER: S-EPMC6785836 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature