Population-based volume kinetics of Ringer's lactate solution in patients undergoing open gastrectomy.

ABSTRACT: In order to maintain stable blood pressure and heart rate during surgery, anesthesiologists need to administer the appropriate amount of fluid with appropriate fluid type to the patient, then quantifying how fluid is distributed and eliminated from the body is useful for establishing a fluid administration strategy. In this study we characterized the volume kinetics of Ringer's lactate solution in patients undergoing open gastrectomy. When propofol and remifentanil reached a pseudosteady state at the target concentration and blood pressure was stabilized following surgical stimulation, enrolled patients were administered 1000 mL of Ringer's lactate solution for 20 min, followed by continuous infusion at a rate of 6 mL/kg/h until the time of the last blood collection for volume kinetic anal

SUBMITTER: Lee JH 

PROVIDER: S-EPMC6786407 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature