Does antibiotic use accelerate or retard cutaneous repair? A systematic review in animal models.

ABSTRACT:

Background

The presence of infections is one of the main factors that leads to delays in healing or non-closure of cutaneous wounds. Although the goal of antibiotic use is to treat or prevent infection, there is currently no agreement on the effectiveness of these products.

Aim

The aim of this study was to evaluate the efficacy of antibiotic use during the healing process of skin wounds in animal models not intentionally infected, as well as to analyze the advances and limitations of the studies carried out in this field.

Main methods

This systematic review was performed according to the PRISMA guidelines, using a structured search on the MedLine (PubMed) and Scopus platforms to retrieve studies published until August 29, 2018, 13:35p.m. The studies included were limi

SUBMITTER: Altoe LS 

PROVIDER: S-EPMC6786583 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature