Pathogen surveillance in the informal settlement, Kibera, Kenya, using a metagenomics approach.

ABSTRACT:

Background

Worldwide, the number of emerging and re-emerging infectious diseases is increasing, highlighting the importance of global disease pathogen surveillance. Traditional population-based methods may fail to capture important events, particularly in settings with limited access to health care, such as urban informal settlements. In such environments, a mixture of surface water runoff and human feces containing pathogenic microorganisms could be used as a surveillance surrogate.

Method

We conducted a temporal metagenomic analysis of urban sewage from Kibera, an urban informal settlement in Nairobi, Kenya, to detect and quantify bacterial and associated antimicrobial resistance (AMR) determinants, viral and parasitic pathogens. Data were examined in conjunction with data

SUBMITTER: Hendriksen RS 

PROVIDER: S-EPMC6786639 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature