Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand.

ABSTRACT: Questions have been raised over the acceptability of conducting human challenge studies in low and middle income countries (LMICs). Most of these concerns are based on theoretical considerations and there exists little data on the attitudes of stakeholders in these countries. This study examines the view of researchers and REC members in Thailand regarding the design and conduct of challenge studies in the country. A questionnaire was developed based on ethical frameworks for human challenge studies. The target respondents included those who had experience with health-related research at universities, non-university hospitals, and research institutes. A total of 240 respondents completed the on-line survey. In general, the respondents felt that the ethical issues raised by human challenge

SUBMITTER: Kaewkungwal J 

PROVIDER: S-EPMC6786649 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature