Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: A systematic review and meta-analysis.

ABSTRACT:

Context

Whether all degrees of periventricular leukomalacia (PVL) and peri-intraventricular haemorrhage (PIVH) have a negative impact on neurodevelopment.

Objective

To determine the impact of PVL and PIVH in the incidence of cerebral palsy, sensorineural impairment and development scores in preterm neonates. Registered in PROSPERO (CRD42017073113).

Data sources

PubMed, Embase, SciELO, LILACS, and Cochrane databases.

Study selection

Prospective cohort studies evaluating neurodevelopment in children born preterm which performed brain imaging in the neonatal period.

Data extraction

Two independent researchers extracted data using a predesigned data extraction sheet.

Statistical methods

A random-effects model was used, with Mantel-Haenszel approach an

SUBMITTER: Gotardo JW 

PROVIDER: S-EPMC6786801 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature