Systematic improvement of isobutanol production from D-xylose in engineered Saccharomyces cerevisiae.

ABSTRACT: As the importance of reducing carbon emissions as a means to limit the serious effects of global climate change becomes apparent, synthetic biologists and metabolic engineers are looking to develop renewable sources for transportation fuels and petroleum-derived chemicals. In recent years, microbial production of high-energy fuels has emerged as an attractive alternative to the traditional production of transportation fuels. In particular, the Baker's yeast Saccharomyces cerevisiae, a highly versatile microbial chassis, has been engineered to produce a wide array of biofuels. Nevertheless, a key limitation of S. cerevisiae is its inability to utilize xylose, the second most abundant sugar in lignocellulosic biomass, for both growth and chemical production. Therefore, the development of a r

SUBMITTER: Promdonkoy P 

PROVIDER: S-EPMC6787123 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature