Minimization of energy transduction confers resistance to phosphine in the rice weevil, Sitophilus oryzae.

ABSTRACT: Infestation of phosphine (PH₃) resistant insects threatens global grain reserves. PH₃ fumigation controls rice weevil (Sitophilus oryzae) but not highly resistant insect pests. Here, we investigated naturally occurring strains of S. oryzae that were moderately resistant (MR), strongly resistant (SR), or susceptible (wild-type; WT) to PH₃ using global proteome analysis and mitochondrial DNA sequencing. Both PH₃ resistant (PH₃-R) strains exhibited higher susceptibility to ethyl formate-mediated inhibition of cytochrome c oxidase than the WT strain, whereas the disinfectant PH₃ concentration time of the SR strain was much longer than that of the MR strain. Unlike the MR strain, which showed altered expression levels of genes en

SUBMITTER: Kim K 

PROVIDER: S-EPMC6787191 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature