Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial.

ABSTRACT:

Rationale

In critically ill patients receiving invasive mechanical ventilation (MV), research supports the use of daily screening to identify patients who are ready to undergo a spontaneous breathing trial (SBT) followed by conduct of an SBT. However, once daily (OD) screening is poorly aligned with the continuous care provided in most intensive care units (ICUs) and the best SBT technique for clinicians to use remains controversial.

Objectives

To identify the optimal screening frequency and SBT technique to wean critically ill adults in the ICU.

Methods

We aim to conduct a multicenter, factorial design randomized controlled trial with concealed allocation, comparing the effect of both screening frequency (once versus at least twice daily [ALTD]) and SBT technique (Pr

SUBMITTER: Burns KEA 

PROVIDER: S-EPMC6787986 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature