Predictive performance of the estimating equations of renal function in Sri Lankan subjects.

ABSTRACT:

Objectives

This study validates two popular predictive equations of renal function firstly, Modifications of Diet in Renal Disease and secondly, Chronic Kidney Disease Epidemiology Collaboration equations for Sri Lankan cohort. We used data of the patients referred to Renal Research lab of University of Colombo for creatinine clearance measurement.

Results

Predictive performances varied with the gender. Creatinine clearance and predicted renal functions were compared. Both fared unsatisfactorily with R² ranging from 0.632 to 0.652, and overestimated renal function by 6-15%. The proportion chronic kidney disease staging 1 and 2 returned by Chronic Kidney Disease Epidemiology Collaboration equation showed significant difference, in females. Modifications of Diet in

SUBMITTER: Weerakkody RM 

PROVIDER: S-EPMC6788101 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature