Risk of ischemic stroke and utility of CHA₂ DS₂ -VASc score in women and men with atrial fibrillation.

ABSTRACT:

Background

The magnitude of increased risk of stroke in women with atrial fibrillation (AF) remains uncertain.

Hypothesis

We investigated the risk of ischemic stroke and death in women and men with AF, and the risk associated with individual non-sex CHA₂ DS₂ -VASc risk factors.

Methods

Retrospective cohort study of 231 077 (48.1% women) nonselected patients with AF not receiving oral anticoagulation from 2006 to 2014. Data from cross-linked national Swedish registers. The outcome was the first occurrence of ischemic stroke or death. Median age was 82 and 75 years in women and men, respectively. Mean follow-up was 2.5 years.

Results

Hazard ratios, adjusted for non-sex CHA₂ DS₂ -VASc risk factors, for women vs men were

SUBMITTER: Tomasdottir M 

PROVIDER: S-EPMC6788468 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature