Bioelectrical impedance analysis of body composition for the anesthetic induction dose of propofol in older patients.

ABSTRACT:

Background

Older people are currently the fastest growing segment of the worldwide population. The present study aimed to estimate propofol dose in older patients based on size descriptors measured by bioelectrical impedance analysis (BIA).

Methods

A cross sectional study in adult and older patients with body mass index equal to or lower than 35 kg/m² was carried out. BIA and Clinical Frail Scale scoring were performed during pre-operative evaluation. Propofol infusion was started at 2000 mg/h until loss of consciousness (LOC) which was defined by "loss of eye-lash reflex" and "loss of response to name calling". Total dose of propofol at LOC was recorded. Propofol plasma concentration was measured using gas chromatography/ion trap-mass spectrometry.

Results

SUBMITTER: Araujo AM 

PROVIDER: S-EPMC6790019 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature