Comparing the burdens of opportunistic infections among patients with systemic rheumatic diseases: a nationally representative cohort study.

ABSTRACT:

Objective

To estimate and compare the burdens of opportunistic infections and herpes zoster in real-world practice among patients with various systemic rheumatic diseases.

Methods

This 13-year cohort study used national health insurance data to compare the incidence rates (IRs) of nine opportunistic infections among patients with five rheumatic diseases. The analyses were stratified according to follow-up duration using Poisson regression, and Cox models were used to compare the risk of first opportunistic infection.

Results

During 2000-2013, we identified 76,966 patients who had polymyositis/dermatomyositis (PM/DM, 2270 cases), systemic lupus erythematosus (SLE, 15,961 cases), systemic sclerosis (SSc, 2071 cases), rheumatoid arthritis (RA, 38,355 cases), or primary S

SUBMITTER: Hsu CY 

PROVIDER: S-EPMC6790041 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature