Subcomponent Self-Assembly of a Cyclic Tetranuclear Fe^II Helicate in a Highly Diastereoselective Self-Sorting Manner.

ABSTRACT: An enantiomerically pure diamine based on the 4,15-difunctionalized [2.2]paracyclophane scaffold and 2-formylpyridine self-assemble into an optically pure cyclic metallosupramolecular Fe₄ L₆ helicate upon mixing with iron(II) ions in a diastereoselective subcomponent self-assembly process. The cyclic assembly results from steric strain that prevents the formation of a smaller linear dinuclear triple-stranded helicate, and hence, leads to the larger strain-free assembly that fulfils the maximum occupancy rule. Interestingly, use of the racemic diamine also leads to a racemic mixture of the homochiral cyclic helicates as the major product in a highly diastereoselective narcissistic chiral self-sorting manner given the fact that the assembly contains ten stereogenic elem

SUBMITTER: Anhauser J 

PROVIDER: S-EPMC6790559 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature