A Systematic Review and Guide to Mechanical Testing for Articular Cartilage Tissue Engineering.

ABSTRACT: Articular cartilage is integral to the mechanical function of many joints in the body. When injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have been developed in recent decades to treat damaged cartilage. Given that the primary function of articular cartilage is mechanical in nature, rigorous physical evaluation of cartilage tissues undergoing treatment and cartilage constructs intended for replacement is an absolute necessity. With the large number of groups developing cartilage tissue engineering strategies, however, a variety of mechanical testing protocols have been reported in the literature. This lack of consensus in testing methods makes comparison between studies difficult at times, and can lead to misinterpretation of data relative to nati

SUBMITTER: Patel JM 

PROVIDER: S-EPMC6791482 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature