Impaired relational memory in the early stage of psychosis.

ABSTRACT:

Background

Humans constantly take in vast amounts of information, which must be filtered, flexibly manipulated, and integrated into cohesive relational memories in order to choose relevant behaviors. Relational memory is impaired in chronic schizophrenia, which has been linked to hippocampal dysfunction. It is unclear whether relational memory is impaired in the early stage of psychosis.

Methods

We studied eye movements during a face-scene pairs task as an indirect measure of relational memory in 89 patients in the early stage of psychosis and 84 healthy control participants. During testing, scenes were overlaid with three equally-familiar faces and participants were asked to recall the matching (i.e. previously-paired) face. During Match trials, one face had been previously

SUBMITTER: Avery SN 

PROVIDER: S-EPMC6791765 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature